What regulatory lists does my account cross reference?
Below you will find a comprehensive list of all of the Regulatory Lists against which Chemical Management cross-references ingredients.
Note: Lists marked “Dormant” are lists that are either no longer in use, no longer exist, or were rolled into another regulatory list. The last known iterations of these lists still appear in the Chemical Management product and are cross-referenced via the last available data on the dormant regulatory list.
* List is included with SDS Management accounts.
** List includes additional data in the Master Chemical List and on the Regulatory List Report.
The concentration in air that should not be exceeded during any part of the working exposure. Ceiling limits may supplement other limits or standalone. Developed by the American Conference of Governmental Industrial Hygienists. Also part of the OSHA Z-1 Table.
Date reviewed/updated: 09/08/2024 (updated)
A 15-minute time-weighted average exposure that should not be exceeded at any time during a workday. The units of measures for the threshold limit values are ppm and mg/m3. The TLVs for aerosols are expressed usually in mg/m3. The TLVs for gases and vapors are expressed in ppm or mg/m3. Developed by the American Conference of Governmental Industrial Hygienists. Also part of the OSHA Z-1 Table.
Date reviewed/updated: 09/08/2024 (updated)
The TWA concentration for a conventional 8-hour workday and a 40-hour workweek, to which it is believed that nearly all workers may be repeatedly exposed, day after day, for a working lifetime without adverse effect. Developed by the American Conference of Governmental Industrial Hygienists. Also, part of the OSHA Z-1 Table.
Date reviewed/updated: 09/08/2024 (updated)
The AD-DSL is a list of substances subject to supplier substance reporting in the aerospace and defense supply chain. IAEG® (International Aerospace Environmental Group) has identified regulated chemical substances of concern to the international aerospace and defense industry that are subject to current use, product content restrictions, or reporting requirements with potential impacts on the industry or its customers. The AD-DSL is used for supplier reporting of chemical substances that are included in its products, are used in the production of those products, or are required for operation or maintenance of those products.
Date reviewed/updated 26/07/2024 (updated)
This Restricted Substance List (RSL) was created by a special working group of the American Apparel & Footwear Association’s (AAFA) Environmental Task Force. The RSL is intended to provide apparel and footwear companies with information related to regulations and laws that restrict or ban certain chemicals and substances in finished home textile, apparel, and footwear products around the world. This RSL was developed to serve as a practical tool to help those individuals in textile, apparel, and footwear companies, and their suppliers, responsible for environmental compliance throughout the supply chain, to become more aware of various national and international regulations governing the amount of substances that are permitted in finished home textile, apparel, and footwear products.
Date reviewed/updated 26/07/2024 (reviewed)
Agency for Toxic Substances and Disease Registry Division of Toxicology and Environmental Medicine. The Priority List of Hazardous Substances includes substances that have been determined to be of greatest public health concern to persons at or near NPL sites. CERCLA, as amended, also requires that the Priority List of Hazardous Substances be revised periodically.
Date reviewed/updated: 26/10/2022 (updated)
The CERS Data Registry (CDR) provides a listing of data fields used by the California Environmental Reporting System (CERS).
Date reviewed/updated 26/07/2024 (reviewed)
The substances on the California Hazardous Substances List are subject to the provisions of California Labor Code Sections 6360 through 6399.7 and Section 5194 in Title 8, Sec. 339 of the California Code of Regulations. Companies are required to provide information about the location of hazardous materials release sites, for use in filing permits, Tier II reporting and the state’s mandated Hazardous Materials Business Plan.
Date reviewed/updated: 26/07/2024 (reviewed)
California Proposition 65 requires all covered employers to provide a warning about the hazards of any substance included in Title 22 California Code of Regulations §12000 (Safe Drinking Water and Toxic Enforcement Act of 1986) present in the employer’s establishment. The Proposition was intended by its authors to protect California citizens and the State’s drinking water sources from chemicals known to cause cancer, birth defects, or other reproductive harm, and to inform citizens about exposures to such chemicals. The decision to provide a Proposition 65 warning is made by the respective business based upon its knowledge of the types of chemical exposures it is responsible for causing to individuals. A business is not required to notify our office or any other regulatory agency when it decides to provide a warning.
Date reviewed/updated: 10/03/2025 (updated)
In 2008, the California legislature passed the Green Chemistry law which authorizes and requires the Department of Toxic Substances Control (DTSC) to adopt regulations to establish a process to identify and prioritize chemicals in consumer products and to establish a process for evaluating chemicals of concern in consumer products and their potential safer alternatives.
Date reviewed/updated: 26/07/2024 (updated)
Substances identified as Toxic Air Contaminants, known to be emitted in California, reviewed by the Scientific Review Panel. Includes Category 1, 2a, 2b, 3ab, 4a, 4b, 5 and 6 data.
Date reviewed/updated: 08/07/2024 (reviewed)
California OSHA has established an extensive list of Permissible Exposure Limits (PELs) that are enforced in workplaces under its jurisdiction. Though not enforceable in establishments outside of California, the PELs can provide information on acceptable levels of chemicals in the workplace. Also part of the OSHA Z-1 Table.
Date reviewed/updated: 08/07/2024 (reviewed)
California OSHA has established an extensive list of Short Term Exposure Limits (STELs) that are enforced in workplaces under its jurisdiction. Though not enforceable in establishments outside of California, the STELs can provide information on acceptable levels of chemicals in the workplace. Also part of the OSHA Z-1 Table.
Date reviewed/updated: 08/07/2024 (reviewed)
The Canadian Environmental Protection Act (CEPA) authorizes the Ministers of Health and the Environment to conduct research and collect information on a wide variety of substances that may contaminate the environment or cause adverse effects on human health and/or the environment. If a substance is determined to be ”toxic,” as per CEPA 1999, Environment Canada and Health Canada are then responsible for implementing preventive and/or control actions for any or all phases of that substance’s ”life cycle.” This is done to prevent or control the substance’s release into the environment; the substance(s) are subsequently added to CEPA, 1999, Schedule 1, List of Toxic Substances.
Date reviewed/updated: 05/05/2023 (reviewed)
A compilation of about 23,000 substances used, imported or manufactured in Canada for commercial purposes. It includes discrete organic compounds, inorganic substances, organometallic substances, polymers, and unknown or variable composition complex reaction products or biological material such as acetone or iron.
Date reviewed/updated: 27/03/2025 (updated)
The Domestic Substances List (DSL) and the Non-Domestic Substances List (NDSL) were created in accordance with the Canadian Environmental Protection Act (CEPA) by Environment Canada. The DSL defines “existing” substances for the purposes of implementing CEPA and is the sole basis for determining whether a substance is “existing” or “new” to Canada. The NDSL specifies substances, other than those on the DSL, that were in world commerce, but not in Canada, and is based on the US Environmental Protection Agency’s (EPA’s) 1985 inventory compiled for the Toxic Substances Control Act (TSCA). Substances that are not on the DSL may require notification and assessment before they can be manufactured or imported into Canada. Substances on the NDSL have different notification requirements.
Date reviewed/updated: 17/05/2023 (updated)
The NPRI is the national Pollutant Release and Transfer Register of Canada – a publicly-accessible inventory used to track and catalog the release of pollutants, their disposal, or their transfer to recycling and other facilities across the country. Facilities that meet reporting requirements are required to report to the NPRI under the Canadian Environmental Protection Act (CEPA), 1999. All pollutants released to air, water, and/or land are tracked.
Date reviewed/updated: 21/03/2025 (updated)
This list is published by the Centers for Disease Control and Prevention (CDC) and lists substances NIOSH considers to be potential occupational cancer-causing agents. NIOSH recommends workplace exposure limits and appropriate preventive measures to reduce or eliminate adverse health effects and accidental injuries. Some of the potential carcinogens listed in this index may be re-evaluated by NIOSH as new data become available and the NIOSH recommendations on these carcinogens either as to their status as a potential occupational carcinogen or as to the appropriate recommended exposure limit may change.
Date reviewed/updated: 12/05/2023 (reviewed)
The Chemical Weapons Convention aims to eliminate an entire category of weapons of mass destruction by prohibiting the development, production, acquisition, stockpiling, retention, transfer or use of chemical weapons States Parties. States Parties, in turn, must take the steps necessary to enforce that prohibition in respect of persons (natural or legal) within their jurisdiction. Chemicals and substances from all three schedules of the Chemical Weapons Convention are included as part of Chemical Management regulatory list reporting. For additional detail, visit the Organization for the Prohibition of Chemical Weapons website.
Date reviewed/updated: 07/07/2024 (reviewed)
The Chinese Ministry of Industry and Information Technology published this regulation in early 2016, and it is set to come into force July 1st, 2016. Among other things, the regulation restricts the concentration of listed hazardous substances in electronic and electrical products.
Date reviewed/updated: 07/07/2024 (reviewed)
The Cosmetic Ingredient Review (CIR) studies individual chemical compounds as they are used in cosmetic products. CIR relies heavily on the International Nomenclature of Cosmetic Ingredients (INCI) when identifying the ingredients to be assessed. The CIR procedure created an expert panel to set priorities and review and assess ingredient safety data. The panel conducts extensive literature searches, compiles data, and prepares draft reports on high-priority ingredients. They organize the literature into several categories: chemistry, use, general biology, and animal toxicology. They also prepare a clinical assessment of the ingredients that may include epidemiologic studies, along with classic repeated insult patch tests.
Date reviewed/updated: 26/05/2023 (reviewed)
The Cosmetic Ingredient Review (CIR) studies individual chemical compounds as they are used in cosmetic products. CIR relies heavily on the International Nomenclature of Cosmetic Ingredients (INCI) when identifying the ingredients to be assessed. The CIR procedure created an expert panel to set priorities and review and assess ingredient safety data. The panel conducts extensive literature searches, compiles data, and prepares draft reports on high-priority ingredients. They organize the literature into several categories: chemistry, use, general biology, and animal toxicology. They also prepare a clinical assessment of the ingredients that may include epidemiologic studies, along with classic repeated insult patch tests.
Date reviewed/updated: 26/05/2023 (reviewed)
The Cosmetic Ingredient Review (CIR) studies individual chemical compounds as they are used in cosmetic products. CIR relies heavily on the International Nomenclature of Cosmetic Ingredients (INCI) when identifying the ingredients to be assessed. The CIR procedure created an expert panel to set priorities and review and assess ingredient safety data. The panel conducts extensive literature searches, compiles data, and prepares draft reports on high-priority ingredients. They organize the literature into several categories: chemistry, use, general biology, and animal toxicology. They also prepare a clinical assessment of the ingredients that may include epidemiologic studies, along with classic repeated insult patch tests.
Date reviewed/updated: 26/05/2023 (reviewed)
The Cosmetic Ingredient Review (CIR) studies individual chemical compounds as they are used in cosmetic products. CIR relies heavily on the International Nomenclature of Cosmetic Ingredients (INCI) when identifying the ingredients to be assessed. The CIR procedure created an expert panel to set priorities and review and assess ingredient safety data. The panel conducts extensive literature searches, compiles data, and prepares draft reports on high-priority ingredients. They organize the literature into several categories: chemistry, use, general biology, and animal toxicology. They also prepare a clinical assessment of the ingredients that may include epidemiologic studies, along with classic repeated insult patch tests.
Date reviewed/updated: 26/05/2023 (reviewed)
The Cosmetic Ingredient Review (CIR) studies individual chemical compounds as they are used in cosmetic products. CIR relies heavily on the International Nomenclature of Cosmetic Ingredients (INCI) when identifying the ingredients to be assessed. The CIR procedure created an expert panel to set priorities and review and assess ingredient safety data. The panel conducts extensive literature searches, compiles data, and prepares draft reports on high-priority ingredients. They organize the literature into several categories: chemistry, use, general biology, and animal toxicology. They also prepare a clinical assessment of the ingredients that may include epidemiologic studies, along with classic repeated insult patch tests.
Date reviewed/updated: 26/05/2023 (reviewed)
The United States Drug Enforcement Administration (DEA) Chemical Control Program seeks to reduce the supply of illicit drugs and diverted chemicals by disrupting and dismantling the operations and financial infrastructures of major trafficking organizations. DEA registration, record keeping and suspicious order reporting requirements apply to importers, exporters, manufacturers, distributors and certain retailers of listed chemicals. List I chemical means a chemical that, in addition to legitimate uses, is used in manufacturing a controlled substance in violation of the Controlled Substances Act and is important to the manufacture of a controlled substance.
Date reviewed/updated: 27/11/2024 (updated)
The United States Drug Enforcement Administration (DEA) Chemical Control Program seeks to reduce the supply of illicit drugs and diverted chemicals by disrupting and dismantling the operations and financial infrastructures of major trafficking organizations. DEA registration, record keeping and suspicious order reporting requirements apply to importers, exporters, manufacturers, distributors and certain retailers of listed chemicals. List II chemical means a chemical, other than a List I chemical, that, in addition to legitimate uses, is used in manufacturing a controlled substance in violation of the Controlled Substances Act.
Date reviewed/updated: 05/07/2024 (reviewed)
he Department of Homeland Security (DHS) issues a Chemicals of Interest (COI) list as Appendix A to the Chemical Facility Anti-Terrorism Standards (CFATS), which covers any facility that manufactures, uses, stores, or distributes certain chemicals at or above a specified quantity that are deemed by the department to be a potential security threat. If the chemicals possessed by a facility are above the Specified threshold quantity, a requirement is triggered to complete and submit an easy-to-use, online consequence assessment tool called a Top-Screen. Using the information gathered through the Top-Screen, the department will be better able to make a preliminary determination as to whether a facility presents a high level of security risk and whether it will be required to comply with the substantive requirements of CFATS.
Date reviewed/updated: 01/07/2024 (reviewed)
The EPA is required to control 187 hazardous air pollutants. The 1990 Clean Air Act Amendments direct the Environmental Protection Agency (EPA) to set standards for all major sources of air toxics (and some area sources that are of particular concern). Thus, the EPA is required to control a listing of hazardous air pollutants, also known as toxic air pollutants or air toxins. These pollutants cause or may cause cancer or other serious health effects, such as reproductive effects or birth defects, or adverse environmental and ecological effects.
Date reviewed/updated: 05/07/2024 (reviewed)
The substances on the EPA Clean Water Act Priority Pollutant list can be subject to several different kinds of regulatory activity, some based on considerations of water quality and some based on the technologies available for pollution control in different industrial sectors. The Environmental Protection Agency establishes criteria for the quality of ambient water (lakes and streams, for example) that identify the concentration levels of specific chemicals that will not pose unacceptable risks to human or aquatic life. These criteria are not enforceable legal standards. However, they can serve as the scientific foundation of water quality standards set by states, which are enforceable. Separately, U.S. EPA also sets limits on the discharge of priority pollutants (“effluent limits”) by various types of industries.
Date reviewed/updated: 05/07/2024 (reviewed)
These lists include specific commercial chemical products in an unused form. Some pesticides and some pharmaceutical products become hazardous waste when discarded. Wastes included on the P-lists can be found in the regulations at 40 CFR §261.33.
Date reviewed/updated: 29/04/2025 (reviewed)
This EPA-controlled list assists in compliance with the Clean Air Act (CAA) 112(r) chemical accident release prevention requirements. It details controlled toxic substances and threshold quantities in an effort to prevent the accidental release of regulated substances and other extremely hazardous substances into the air. The list is publicized to minimize the consequences of such releases if they do occur by emphasizing preventative measures for chemicals believed to pose the greatest risk. The regulation includes a List of Regulated Substances under section 112(r) of the Clean Air Act, including their synonyms and threshold quantities (in pounds) to help assess if a process is subject to the RMP rule or the general duty clause. States who have taken delegation of the Clean Air Act, Section 112(r) program may have additional requirements for the federally listed chemicals, and/or additional listed chemicals. Owners and operators of a facility (stationary source) that manufactures, uses, stores, or otherwise handles more than a threshold quantity of a listed regulated substance in a process, must implement a risk management program and submit a single RMP for all covered processes at the facility. “Process” means any activity involving a listed regulated substance, including any use, storage, manufacturing, handling, or on-site movement of such substances, or combination of these activities.
Date reviewed/updated: 29/04/2025 (reviewed)
This EPA-controlled list assists in compliance with the Clean Air Act (CAA) 112(r) chemical accident release prevention requirements. It details controlled flammable substances to prevent the accidental release of regulated substances and other extremely hazardous substances into the air. The list is publicized to minimize the consequences of such releases if they do occur by emphasizing preventative measures for chemicals believed to pose the greatest risk. The regulation includes a List of Regulated Substances under section 112(r) of the Clean Air Act, including their synonyms and threshold quantities (in pounds) to help assess if a process is subject to the RMP rule or the general duty clause. States who have taken delegation of the Clean Air Act, Section 112(r) program may have additional requirements for the federally listed chemicals, and/or additional listed chemicals. Owners and operators of a facility (stationary source) that manufactures, uses, stores, or otherwise handles more than a threshold quantity of a listed regulated substance in a process, must implement a risk management program and submit a single RMP for all covered processes at the facility. “Process” means any activity involving a listed regulated substance, including any use, storage, manufacturing, handling, or on-site movement of such substances, or combination of these activities.
Date reviewed/updated: 29/04/2025 (reviewed)
EPA’s CompTox Chemicals Dashboard contains chemistry, toxicity and exposure information for over one million chemicals, with over 300 chemical lists based on structure or category. Per- and poly-fluoroalkyl substances (PFAS) are identified by several lists. This list consists of chemicals with explicit chemical structures assigned and filtered for PFAS based on molecular structure and formula.
Date reviewed/updated: 27/03/2025 (reviewed)
EPA’s CompTox Chemicals Dashboard contains chemistry, toxicity and exposure information for over one million chemicals, with over 300 chemical lists based on structure or category. Per- and poly-fluoroalkyl substances (PFAS) are identified by several lists. This list consists of PFAS chemicals without explicit chemical structures, including polymers and other chemicals of Unknown or Variable composition, Complex reaction products and Biological materials (UVCB).
Date reviewed/updated: 27/03/2025 (reviewed)
The TCLP, or Toxicity Characteristic Leaching (not Leachate) Procedure (D-Codes) is designed to determine the mobility of both organic and inorganic analytes present in liquid, solid, and multiphasic wastes. This is usually used to determine if a waste may meet the definition of EP Toxicity, that is, carrying a hazardous waste code under RCRA (40 CFR Part 261) of D004 through D052. As it is the generator’s responsibility to make this determination, but generators often contract outside labs to perform the TCLP test, these questions and answers may be helpful to generators. For this reason and sometimes in cleanup actions, businesses are often asked to perform an analysis on their waste using the TCLP. The Code of Federal Regulations (CFR).
Date reviewed/updated: 29/04/2025 (reviewed)
These lists include specific commercial chemical products in an unused form. Some pesticides and some pharmaceutical products become hazardous waste when discarded. Wastes included on the U-list can be found in the regulations at 40 CFR §261.33.
Date reviewed/updated: 29/04/2025 (reviewed)
The Safe Drinking Water Act (SDWA) requires EPA to list unregulated contaminants which are known or anticipated to occur in public water systems, and which may require a national drinking water regulation in the future. Every five years, EPA must publish a list of contaminants called the Contaminant Candidate List (CCL). After publishing, EPA must also decide whether to regulate at least five contaminants from the list (called Regulatory Determinations). EPA uses the CCL to prioritize research and data collection efforts to inform the Agency’s decision on whether we should regulate a specific contaminant.
Date reviewed/updated: 05/07/2024 (reviewed)
The Emergency Planning and Community Right-to-Know Act (EPCRA) of 1986, Section 302(c), is the Emergency Planning Notification requirement for chemicals listed on the extremely hazardous substances list. Facilities housing or using the listed chemicals at or above the set threshold planning quantity must notify the State Emergency Response Commission (SERC) and Local Emergency Planning Committee (LEPC) within 60 days after they first receive a shipment or product the substance on site. The facility also must notify the LEPC of a facility representative who will participate in the emergency planning process. Upon request from the LEPC, the facility shall promptly provide information to the LEPC necessary for developing and implementing the emergency plan.
Date reviewed/updated: 04/08/2024 (reviewed)
The list of reportable chemicals are known to potentially cause acute human health risks, cancer, or chronic (non-cancer) human health effects and/or environmental effects, and are also referred to as the Toxic Release Inventory, or TRI list. Under Section 313 of the Emergency Planning and Community Right-to-Know Act, certain businesses are required to submit reports each year on the amounts of EPCRA section 313 chemicals their facilities released into the environment (either routinely or as a result of accidents), or otherwise managed as waste. The purpose of this reporting requirement is to inform the public about the releases and other waste management of EPCRA section 313 chemicals in their communities and to provide the government with information for research and the development of appropriate regulations. Section 313 requires facilities to report for each listed chemical the amount released to air, water, land, underground injection, and transferred off-site to disposal. Facilities also must report the amounts of those EPCRA section 313 chemicals otherwise managed as waste, including on-site treatment, combustion for energy recovery, recycling and transfers offsite for treatment, combustion for energy recovery, and recycling.
Date reviewed/updated: 01/01/2025 (updated)
The Eugene Toxics Right-to-Know Program was created in 1996 by an amendment to the City of Eugene Charter that requires certain manufacturers to provide information to the public concerning the use and disposition of federally listed hazardous substances. This is a public information program as opposed to a regulatory program. It is overseen by a seven-member volunteer citizen board appointed by the Eugene City Council.
Date reviewed/updated: 17/05/2023 (reviewed)
The RoHS directive took effect on 1 July 2006, and is required to be enforced and become law in each member state. This directive restricts the use of six hazardous materials in the manufacture of various types of electronic and electrical equipment. It is closely linked with the Waste Electrical and Electronic Equipment Directive (WEEE) 2002/96/EC which sets collection, recycling, and recovery targets for electrical goods and is part of a legislative initiative to solve the problem of huge amounts of toxic e-waste. This is also known as the lead-free directive.
Date reviewed/updated: 12/09/2024 (updated)
Provides a definitive list of substances requiring declaration in specific uses, with the target to minimize individual requirements and ensure cost-effective management of declaration practice along the complex automotive supply chain. The GADSL only covers substances that are expected to be present in a material or part that remains in the vehicle or part at the point of sale. The information requirements have to form the basis for further decision-making. The declaration is not intended to automatically lead to substitution as in many “black lists” before. It should foster dialogue, adequate intended use as well as bring certainty through knowledge-based decision making based risk-based evaluations based on robust science. It is important to notice that substances are declarable in their specific use, not based on their hazard only Material declaration is obligatory to ensure compliance with current legislation e.g. environmental protection and recycling. The GADSL is the result of a year-long global effort of representatives from the automotive, automotive parts supplier (tier supplier), and chemical/plastics industries who have organized the Global Automotive Stakeholders Group (GASG). The GASG’s purpose is to facilitate communication and exchange of information regarding the use of certain substances in automotive products throughout the supply chain. The GADSL only covers substances that are expected to be present in a material or part that remains in a vehicle at the point of sale.
Date reviewed/updated: 01/07/2024 (updated)
Lists declarable cancer-causing agents required for Idaho’s Toxic Air Pollutant Emissions Inventory.
Date reviewed/updated: 01/07/2024 (reviewed)
Lists declarable non-cancer-causing agents required for Idaho’s Toxic Air Pollutant Emissions Inventory.
Date reviewed/updated: 01/07/2024 (reviewed)
Lists substances determined by the State of Illinois to potentially cause or significantly contribute to an increase in mortality, an increase in serious irreversible, incapacitating reversible illness, or may pose a significant threat to human health.
Date reviewed/updated: 27/06/2024 (reviewed)
European Union Commission Decision 2006/257/EC of February 9, 2006, amending Decision 96/335/EC, provides an inventory and common nomenclature of ingredients employed in the production of cosmetic products, presented in two parts: Section I – Cosmetic Ingredients Other Than Perfume and Aromatic Raw Materials, and Section II – Perfume and Aromatic Raw Materials. According to the Decision, the inventory is not intended as an authorization for the use of the included substances in the production of cosmetic products, but rather, a listing of chemical substances for which a common nomenclature has been established based on INCI (International Nomenclature Cosmetic Ingredient) standards. Authorizations and limitations on the inclusion of substances in cosmetic products are regulated through the Cosmetics Directive, 76/768/EEC.
Date reviewed/updated: Dormant
European Union Commission Decision 2006/257/EC of February 9, 2006, amending Decision 96/335/EC, provides an inventory and common nomenclature of ingredients employed in the production of cosmetic products, presented in two parts: Section I – Cosmetic Ingredients Other Than Perfume and Aromatic Raw Materials, and Section II – Perfume and Aromatic Raw Materials. According to the Decision, the inventory is not intended as an authorization for the use of the included substances in the production of cosmetic products, but rather, a listing of chemical substances for which a common nomenclature has been established based on INCI (International Nomenclature Cosmetic Ingredient) standards. Authorizations and limitations on the inclusion of substances in cosmetic products are regulated through the Cosmetics Directive, 76/768/EEC.
Date reviewed/updated: Dormant
IARC is an intergovernmental agency forming part of the World Health Organization. The IARC Monographs identify environmental factors, including chemicals, that are carcinogenic hazards to humans. Interdisciplinary working groups of expert scientists review the published studies and assess the strength of the available evidence that an agent can cause cancer in humans. All chemicals appearing in the compendium are included in Chemical Management regulatory cross-reference for this list, so if you require a more detailed understanding of which classification a given chemical has been assigned, visit http://www.iarc.fr/
Date reviewed/updated: 11/08/2024 (reviewed)
Lists materials that may not be used in the ILBC’s directives on sustainable construction. The ILBC is a non-governmental organization (NGO) offering guidelines for the certification of buildings and structures that meet its stringent building and materials rules.
Date reviewed/updated: 25/05/2023 (updated)
IEC 62474:2012 specifies the procedure, content, and form relating to material declarations for products of companies operating in and supplying the electrotechnical industry. Process chemicals and emissions during product use are not in the scope of this International Standard. It provides data to downstream manufacturers that: a) allows them to assess products against substance restriction compliance requirements; b) they can use in their environmentally conscious design process and across all product life cycle phases
Date reviewed/updated: 01/06/2023 (updated)
This list identifies chemicals associated with a Declare Red List ingredient. For more information about Declare labels, products, and the Living Building Challenge visit https://living-future.org/.
Date reviewed/updated: Dormant
Lists both the toxic substances and the flammable substances regulated under the Department of Environmental Quality (DEQ) Chemical Accident Prevention Program. This is a combined list that includes chemicals regulated under both federal and Louisiana state regulatory codes (40 CFR Part 68 and LAC 33:III.Chapter 59, respectively). This rule, which adopted the U.S. Environmental Protection Agency regulation 40 CFR 68 by reference, requires all stationary sources with any of the listed regulated substance(s) above the threshold quantity to submit a Risk Management Plan (RMP).
Date reviewed/updated: Dormant
Maine Department of Environmental Protection lists compounds as chemicals of concern. From this list, chemicals of high concern are designated and upon further review, may be elevated to priority chemical status which results in regulatory action. Each tier of prioritization builds upon the criteria of the list before it. Manufacturers selling certain categories of children’s products in Maine containing any of Maine’s priority chemicals, in an amount greater than de minimis, and who have not already reported to the Department, must do so within 30 days of the product’s availability in Maine.
Date reviewed/updated: 27/06/2024 (reviewed)
Facilities in Maine must report emissions of all hazardous air pollutants that they emit at or above the threshold listed, or where actual emissions are not known, either use, process, or manufacture at or above the published threshold. This includes any hazardous air pollutant coincidentally manufactured, such as byproducts of a process or compounds resulting from combustion.
Date reviewed/updated: 27/06/2024 (reviewed)
The Toxic Air Pollutant (TAP) regulations created to protect the public from TAP emissions from stationary sources of air pollution. These regulations, while not unique in structure to other programs in the United States, are noteworthy due to the number of pollutants considered and the number of sources subject to it.
Date reviewed/updated: 05/06/2023 (reviewed)
TURA requires Massachusetts companies that use large quantities of specific toxic chemicals to evaluate and plan for pollution prevention opportunities, implement them if practical, and annually measure and report the results.
Date reviewed/updated: 08/06/2023 (updated)
The Massachusetts Oil and Hazardous Materials List (MOHML) contains oils and hazardous materials subject to 310 CMR 40.0000 and their reportable quantities (RQs) and reportable concentrations (RCs).
Date reviewed/updated: 27/06/2024 (reviewed)
The pollutant release and transfer register (PRTR), known in Mexico as the Registro de Emisiones y Transferencia de Contaminants (RETC) listing industrial plants and their emissions of 104 different toxic chemicals to the air, water, and land.
Date reviewed/update: 27/06/2024 (reviewed)
The National Inventory of Chemical Substances (INSQ) is standardized and updated information of chemicals sold in the country. It aims to support the management of chemicals in Mexico for health and environmental protection using an exhaustive list of commercial chemicals and their relevant characteristics. The inventory was made available in November 2012. The content of the chemical inventory includes CAS number, chemical synonyms, molecular formula, chemical class, up to 2009 import and production quantities, ecotoxicological information, environmental persistence, bioaccumulation, and toxicity in aquatic organisms.
Date reviewed/updated: 27/06/2024 (reviewed)
The Minnesota Employee Right-To-Know Standard includes lists of hazardous substances, harmful physical agents, and infectious agents to aid employers in evaluating their workplaces. The current Minnesota hazardous substance list contains approximately 750 substances considered by the state as having an occupational exposure risk.
Date reviewed/updated: 27/06/2024 (reviewed)
The Model Toxins in Packaging Legislation was jointly developed under the auspices of the Coalition of Northeast Governors (CONEG) Policy Research Center. The model legislation prohibits the intentional introduction of the four heavy metals, PFAS and phthalates during manufacturing or distribution. The intent was for individual Northeast states to adopt the Model Legislation, and thereby create consistent requirements for the reduction/ eminiation of specific toxins in packaging sold or distributed in the Northeast. Most of the Northeast states passed and implemented laws based on the model and in the subsequent years additional states outside of the region (not all of them became members of TPCH) as well as other countries adapted similar laws based on the model.
Date reviewed/updated: 27/06/2024 (reviewed)
These rules require all major facilities in New Jersey to prepare and submit Discharge Prevention Containment and Countermeasure (DPCC) plans and Discharge Cleanup and Removal (DCR) plans.
Date reviewed/updated: 27/06/2024 (reviewed)
The NHDES Air Toxics Control Program regulates hazardous air pollutants emissions, as well as over 800 regulated toxic air pollutants (RTAPs), which have a health-based risk to humans. The regulatory program aims to protect public health and the environment by establishing ambient air limits (AALs) and requiring businesses in the state to reduce their emissions of any of the RTAPs, such that they do not impact the downwind air quality at levels that may exceed the established AALs. The list of RTAPs, published in NH Code of Administrative Rules Chapter Env-A 1400 Regulated Toxic Air Pollutants includes: (1) those compounds listed as HAPs by EPA; (2) those chemical substances for which a threshold limit value (TLV) has been established by the American Conference of Governmental Industrial Hygienists (ACGIH); and (3) those compounds not otherwise included that are regulated by the Occupational Safety and Health Administration (OSHA).
Date reviewed/updated: 27/06/2024 (reviewed)
Contains any substance or substance contained in a mixture determined by the New Jersey Department of Environmental Protection to pose a threat to the health or safety of employees. This list is integral in completing New Jersey’s annual Right-to-Know Survey, submitted to the Department of Environmental Protection.
Date reviewed/updated: 27/06/2024 (reviewed)
This list is published as required by New York state law and is a list of substances deemed hazardous to the public health, safety, or the environment. Reporting thresholds are set by the Department of Environmental Conservation.
Date Reviewed/Updated: Dormant
The Department of Health establishes the Maximum Contaminant Levels (MCLs) of substances that are allowed in drinking water supplies by adopting or revising EPA standards, or adopting a more stringent standard or guidelines. The rules regarding the drinking water standards are updated periodically.
Date Reviewed/Updated 27/06/2024 (Reviewed)
This list is published as required by New York state law and is a list of substances deemed hazardous to the public health, safety, or the environment. Reporting thresholds are set by the Department of Environmental Conservation.
Date Reviewed/Updated: 27/06/2024 (Reviewed)
The NZIoC is a database of all the hazardous chemical components of products approved under group standards. (Non-hazardous chemicals are not required to be listed.) Many group standards require the hazardous components of products covered under these approvals to be listed on the NZIoC. If you have a new product, you can check the list to see if you comply with the group standard condition. You must notify a new chemical component when the substance containing the new chemical is first imported or manufactured in New Zealand.
Date reviewed/updated: 25/05/2023 (updated)
National Institute for Occupational Safety and Health recommended exposure limits are 8-hr or 10-hr TWA or ceiling concentrations. Also part of the OSHA Z-1 Table.
Date reviewed/updated: 27/06/2024 (reviewed)
The National Institute for Occupational Safety and Health (NIOSH) List of Hazardous Drugs in Healthcare Settings is a tool designed to assist healthcare workers and employers in identifying which drugs routinely handled by employees are considered by NIOSH to be hazardous drugs. NIOSH’s list of hazardous drugs in healthcare builds on a NIOSH alert from 2004 that warned healthcare employers and workers of the risks of working with hazardous drugs and discussed measures they could take to protect their health.
Date reviewed/updated: 10/03/2025 (updated)
National Institute for Occupational Safety and Health short-term exposure limits. Also part of the OSHA Z-1 Table.
Date reviewed/updated: 27/06/2024 (reviewed)
The North Carolina Toxic Air Pollutants (TAPs) list provides a summary of pollutants required to be reported to the North Carolina Division of Air Quality. TAPs are compounds that carry the potential for adverse health effects at certain ambient levels established by the SAB. North Carolina regulates 105 TAPs under its toxic air pollutant control program.
Date reviewed/updated: 27/06/2024 (reviewed)
The U.S. Department of Health and Human Services (HHS) National Toxicology Program (NTP) Report on Carcinogens is a congressionally mandated, science-based public health document. This cumulative report includes listings of substances — chemical, physical, and biological agents; mixtures; and exposure circumstances — that are known or reasonably anticipated to cause cancer in humans.
Date reviewed/updated: 27/06/2024 (reviewed)
The Organisation for Economic Co-operation and Development (OECD) is an international organisation with the goal to shape policies that foster prosperity, equality, opportunity and well-being for all. The OECD Portal on Per- and Polyfluoroalkyl Substances (PFAS) serves to facilitate the exchange of information in order to support a global transition towards safer alternatives. The OECD developed this list of Per- and Polyfluoroalkyl Substances (PFASs) based on a comprehensive analysis of information available in the public domain.
Date reviewed/updated: 27/03/2025 (reviewed)
Eleven of a previous 12 stand-alone designated substance regulations have been consolidated into one designated substances regulation. Employers must set up control programs for employees to reduce risks associated with exposure to member substances.
Date reviewed/updated: 26/06/2024 (reviewed)
The Cleaner Air Oregon Program launched on April 6, 2016. DEQ and the Oregon Health Authority are tasked with working together to create healthier communities. As part of this effort, DEQ and OHA have initiated a regulatory overhaul of Oregon’s air toxics permitting program to make it health-based.
Date reviewed/updated: 25/06/2024 (reviewed)
This contains a listing of toxic and reactive highly hazardous chemicals which present a potential for a catastrophic event at or above the threshold quantity.
Date reviewed/updated: 25/06/2024 (reviewed)
The Oregon Department of Environmental Quality (DEQ) Water Quality Program’s mission is “to protect, restore, and improve Oregon’s water quality.” The 2007 Oregon Legislature directed DEQ to compile a prioritized list of persistent pollutants (the P³ List) to guide DEQ’s pollution prevention efforts. All of the pollutants on the list have potential to cause harm to human health or aquatic life if they get into the water and thereby have the potential to pose a threat to Oregon’s waters.
Date reviewed/updated: 20/06/2024 (reviewed)
This list contains substances found on the OSHA Annotated Table Z-1 (found here: https://www.osha.gov/dsg/annotated-pels/tablez-1.html) and is currently split into the following lists in HQ RegXR accounts: ACGIH – Threshold Limit Values – Ceilings (TLV-C), ACGIH – Threshold Limit Values – Short Term Exposure Limits (TLV-STEL), CALOSHA – Occupational Exposure Limits – PELS, CALOSHA – Occupational Exposure Limits – STELS, NIOSH Ceiling Limits, NIOSH STELS and OSHA PEL Ceiling Limits.
This list provides exposure limits for air contaminants as found in 29 CFR 1910.1000, Air Contaminants to provide guidance and assistance for developing and managing an air contaminants safety awareness program.
Date reviewed/updated: Dormant
A listing of toxic and reactive highly hazardous chemicals that present a potential for a catastrophic event at or above the threshold quantity and require the development of a comprehensive management program that integrated technologies, procedures, and management practices.
Date reviewed/updated: 20/06/2024 (reviewed)
The permissible exposure limit (PEL or OSHA PEL) is a legal limit in the United States for exposure of an employee to a chemical substance. Also part of the OSHA Z-1 Table.
Date reviewed/updated: 20/06/2024 (reviewed)
This list provides information on compounds recognized as ozone-depleting substances from the US EPA.
Date reviewed/updated: 20/06/2024 (reviewed)
Hazardous substances considered to be special hazardous substances because of their particular toxicity, tumorigenicity, mutagenicity, reproductive toxicity, flammability, explosivity, corrosivity, or reactivity pose a special hazard to health and safety. Pennsylvania’s reporting requirements are defined under Act 1984-159.
Date reviewed/updated: 20/06/2024 (reviewed)
Chemicals listed in Part 1 of Annex I are subject to the export notification procedure; chemicals listed in Part 2 of Annex I, in addition to being subject to export notification procedure, qualify also for the PIC notification procedure. Chemicals listed in Part 3 of Annex I, are subject to the full PIC procedure under the Rotterdam Convention. Chemicals in all three parts are included as part of Chemical Management regulatory reporting for this list. For additional detail, visit the European Chemicals Agency website.
Date reviewed/updated: 10/03/2025 (updated)
Annex V lists the chemicals and articles the use of which is prohibited in the European Union and which shall not be exported. Chemicals and articles listed in Part 1 of Annex V are subject to export ban and belong to the category of persistent organic pollutants; Part 2 of Annex V lists chemicals and articles subject to export ban other than persistent organic pollutants. Chemicals in both parts are included as part of Chemical Management regulatory reporting for this list. For additional detail, visit the European Chemicals Agency website.
Date reviewed/updated: 17/05/2023 (updated)
Under REACH Substances of Very High Concern(SVHC) listed in the Annex XIV “Authorization list” will not be allowed to be used, placed on the market or imported into the EU after a date to be set unless the company is granted an authorization.
Date reviewed/updated: 20/06/2024 (reviewed)
Annex XVII contains restrictions on the manufacture, placing on the market and use of certain dangerous substances, preparations, and articles; consolidation of the restrictions contained in Directive 76/769/EC. A list of chemicals with restrictions on the manufacture, placing in the market, and use. The restrictions procedure is a safety net for substances posing an unacceptable risk to human health or the environment. The basis of the demonstration of the unacceptable risk to human health or the environment on a Community-wide basis will be a risk assessment.
Date reviewed/updated: 11/09/2024 (updated)
The identification of a substance as Substance of Very High Concern (SVHC) and its inclusion in the Candidate List is the first step of the REACH authorization procedure. Substances that are included in the Candidate List have been identified as an SVHC. These substances may have very serious and often irreversible effects on humans and the environment. Substances on the Candidate List may subsequently become subject to authorization by decision of the European Commission.
Date reviewed/updated: 10/03/2025 (updated)
This is a list of publishable phase-in substances under REACH regulation that were registered as of January 24, 2011. The information in the list was provided by companies in registration dossiers. The list is based on the information provided by potential registrants and is not an exhaustive list of substances that must be registered.
Date reviewed/updated: Dormant
The data comes from registration dossiers submitted to ECHA by the date indicated as last update. The Total Tonnage Band is compiled from all the dossiers with two exceptions; any tonnages claimed confidentially and any quantity used as an intermediate to produce a different chemical. The Total Tonnage band published does not necessarily reflect the registered tonnage band.
Date reviewed/updated: 07/06/2023 (updated)
The REACH Regulation requires that ECHA recommends priority substances from the REACH Candidate List for inclusion in the REACH Authorization List. This list of “Submitted Recommendations” is a list of substances that have been recommended for inclusion on the REACH Authorization List. The European Commission will review submission details for each substance, which includes proposals for transition, exemption, and review periods, as well as the opinions of member states. The European Commission eventually decides, by “comitology” procedure (with scrutiny), which substances will be included in Annex XIV and what the associated entries will be.
Date reviewed/updated: 08/08/2024 (updated)
The In Commerce sub-lists were compiled from Health Canada records, and while the In Commerce sub-lists have been a useful administrative tool, they contained duplications, omissions and inaccurate chemical identifiers. As such, Health Canada recognized the need to revise the In Commerce sub-lists in order to address these issues. In September of 2010, a notice of intent to revise the In Commerce sub-lists was published in the Canada Gazette Part I. The revision of the In Commerce sub-lists was carried out through:
- Phase 1: a substance identity verification program within Health Canada, and
- Phase 2: a voluntary nomination process
The nomination process for including substances on the Revised In Commerce List (R-ICL) was completed February 14, 2012. Although the formal nomination process for including substances on the R-ICL has ended, any additional nominations to the R-ICL may be submitted and will be reviewed. Health Canada will update the R-ICL as required.
Date reviewed/updated: 20/06/2024 (reviewed)
Rhode Island Right-to-Know Hazardous Substances List.
Date reviewed/updated: 20/06/2024 (reviewed)
This is a list of chemical substances banned from intentional use in facilities that process textile materials and trim parts in apparel and footwear. ZDHC establishes acceptable concentration limits for substances in chemical formulations used within manufacturing facilities. The limits are designed to eliminate the possibility of intentional use of listed substances. The intent is to manage the input of chemicals to the suppliers and remove those hazardous substances from the manufacturing process. It is a living document and will be updated as needed to expand the materials and processes covered and to add substances that should be phased out of the supply chain. For more information, visit http://www.roadmaptozero.com/
Date reviewed/updated: 20/06/2024 (reviewed)
The Rotterdam Convention creates legally binding obligations for the implementation of the Prior Informed Consent (PIC) procedure.The chemicals listed in Annex III include pesticides and industrial chemicals that have been banned or severely restricted for health or environmental reasons by two or more Parties and which the Conference of the Parties has decided to subject to the PIC procedure. For additional detail, visit the Rotterdam Convention website.
Date reviewed/updated: 20/06/2024 (reviewed)
The SIN (Substitute it Now!) List is a globally used database of chemicals likely to be banned or restricted in a near future. The chemicals on the SIN List have been identified by ChemSec as Substances of Very High Concern based on the criteria established by the EU chemicals regulation REACH. The SIN List aims to spark innovation towards products without hazardous chemicals by speeding up legislative processes and giving guidance to companies and other stakeholders on which chemicals to start substituting.
Date reviewed/updated: 07/03/2025 (reviewed)
The Stockholm Convention on Persistent Organic Pollutants is a global treaty to protect human health and the environment from chemicals that remain intact in the environment for long periods, become widely distributed geographically, accumulate in the fatty tissue of humans and wildlife, and have harmful impacts on human health or on the environment. Exposure to Persistent Organic Pollutants can lead to serious health effects including certain cancers, birth defects, dysfunctional immune and reproductive systems, greater susceptibility to disease, and damages to the central and peripheral nervous systems. Given their long-range transport, no one government acting alone can protect its citizens or its environment from POPs. In response to this global problem, the Stockholm Convention, which was adopted in 2001 and entered into force in 2004, requires its parties to take measures to eliminate or reduce the release of POPs into the environment.
Date reviewed/updated: 20/06/2024 (reviewed)
GLAPS is the result of efforts of a global team from the automotive, automotive suppliers and chemical industries organized in the Automotive Process Substance Group (APSG). The purpose of the APSG is to facilitate communication and exchange of information regarding the use of certain substances in chemical products throughout the supply chain. The GLAPS only contains substances that are relevant to the automotive industry and are delivered to the automotive industry as a substance or mixture. For the full scope please see Document Scope (Annex of Guidance).
Date reviewed/updated: 20/06/2024 (reviewed)
ChemTRAC is a Toronto Public Health program that collects data each year from local businesses and institutions on 25 priority substances that are commonly used or released, and exist in our environment at levels of concern for health. Evidence links these substances to short-term health effects like respiratory problems, and longer-term impacts such as cancer. The program requires local facilities to annually track and report on the use and release of priority substances as per the Environmental Reporting and Disclosure Bylaw (PDF) (Municipal Code Chapter 423). ChemTRAC also supports local facilities with green business practice strategies and provides the public with information on the key chemicals in their community.
Date reviewed/updated: 20/06/2024 (reviewed)
The Toxic Substances Control Act (TSCA), as amended by the Frank R. Lautenberg Chemical Safety for the 21st Century Act, requires EPA to designate chemical substances on the TSCA Chemical Substance Inventory as either “active” or “inactive” in U.S. commerce. To accomplish that, EPA finalized a rule requiring industry reporting of chemicals manufactured (including imported) or processed in the U.S. over the past 10 years, ending on June 21, 2016. This reporting will be used to identify which chemical substances on the TSCA Inventory are active in U.S. commerce and will help inform the prioritization of chemicals for risk evaluation.
Date reviewed/updated: See Toxic Substances Control Act (TSCA Inventory)
The Toxic Substance Control Act (TSCA), as amended by the Frank R. Lautenberg Chemical Safety for the 21st Century Act, requires EPA to designate certain substances reported under 40 CFR 711 as active substances for the purposes of TSCA section 6(b) prioritization for risk evaluations. The Agency has developed a list of active chemical substances that are exempt from reporting under the TSCA Inventory Notifications (Active-Inactive) rule. The Exemption List of Active Substances includes chemical substances reported under the 2012 and 2016 Chemical Data Reporting (CDR) rule, and in Notices of Commencement received since June 21, 2006. With respect to confidential information, persons who manufactured or processed a chemical substance on the confidential portion of the Inventory that was added to the Inventory prior to June 22, 2016 must submit a request to EPA if they wish to maintain an existing claim for protection against disclosure of the specific chemical identity of the substance as confidential.
Date reviewed/updated: See Toxic Substances Control Act (TSCA Inventory)
Regulated by the EPA, this is a listing of existing chemicals currently available for product manufacture in the United States. Chemicals not listed are defined as new chemicals, and the company must provide a Notice of Commencement of Manufacture or Import (NOC) (EPA Form 7710-56) to EPA within 30 calendar days of the date the substance is first manufactured or imported for nonexempt commercial purposes.
Date reviewed/updated: 06/03/2025 (updated)
This list contains the 15-minute time-weighted average short-term (STEL) occupational exposure limits established by the United Kingdom’s Health and Safety Executive (HSE) Fourth Edition of EH40/2005 Workplace Exposure Limits. An occupational exposure limit is an upper limit on the acceptable concentration of a hazardous substance in workplace air for a particular material or class of materials. It is typically set by competent national authorities and enforced by legislation to protect occupational safety and health.
Date reviewed/updated: 20/06/2024 (reviewed)
This list contains the 8-hour time-weighted average (TWA) occupational exposure limits established by the United Kingdom’s Health and Safety Executive (HSE) Fourth Edition of EH40/2005 Workplace Exposure Limits. An occupational exposure limit is an upper limit on the acceptable concentration of a hazardous substance in workplace air for a particular material or class of materials. It is typically set by competent national authorities and enforced by legislation to protect occupational safety and health.
Date reviewed/updated: 20/06/2024 (reviewed)
Act 188, relating to the regulation of toxic substances (2014), establishes a reporting protocol for manufacturers who use certain chemicals in children’s products. Beginning July 1, 2016, manufacturers who use chemicals designated by the State of Vermont as Chemicals of High Concern to Children, must disclose information about these chemicals to the Department of Health. The Department is continuing development and beta-testing of the online reporting system, and launch of the new system is now anticipated for Spring, 2016. Visit the State of Vermont website for more information and updates.
Date reviewed/updated: 29/04/2025 (reviewed)
Under the Children’s Safe Product Act (CSPA), manufacturers of children’s products are required to notify the department of ecology when a chemical of high concern to children (CHCC) is present in their products or if the product contains more than one component, each product component. The CSPA requires the department of ecology in consultation with the department of health to identify a list of chemicals for which manufacturers of children’s products are required to provide notice. The CSPA specifies both the characteristics of these chemicals and the notice requirements.
Date reviewed/updated: 20/06/2024 (reviewed)
A list of hazardous air pollutants, also known as toxic air pollutants or air toxics. These pollutants cause or may cause cancer or other serious health effects, such as reproductive effects or birth defects, or adverse environmental and ecological effects. Facilities are required to submit information on all HAPs emitted to the West Virginia Department of Environmental Protection.
Date reviewed/updated: 20/06/2024 (reviewed)
Reportable air containment levels. Any person owning or operating a facility that emits an air contaminant in quantities above applicable reporting levels, except indirect sources of air pollution, shall annually submit to the department an emission inventory report of annual, actual emissions or, for particulate matter.
Date reviewed/updated: 20/06/2024 (reviewed)
The State of Wisconsin regulates hazardous air contaminants to protect people from air emissions that may cause or significantly contribute to an increase in mortality or an increase in serious irreversible or incapacitating reversible illness or may pose a significant threat to human health or the environment. Facilities must identify air toxins, quantify emissions, and reduce or control emissions where necessary.
Date reviewed/updated: 20/06/2024 (reviewed)
